SDB-005 is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. It is presumed to be an agonist of the CB₁ and CB₂ cannabinoid receptors. SDB-005 is the indazole core analog of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.

1H-Indazole-3-carboxylic acid, 1-pentyl-, 1-naphthalenyl ester [ACD/Index Name]
1-Naphthyl 1-pentyl-1H-indazole-3-carboxylate [ACD/IUPAC Name]
1-Naphthyl-1-pentyl-1H-indazol-3-carboxylat [German] [ACD/IUPAC Name]
1-Pentyl-1H-indazole-3-carboxylate de 1-naphtyle [French] [ACD/IUPAC Name]
1198181-40-6 [RN]
2180934-13-6 [RN]
naphtalen-1-yl-1-pentyl-1H-indazol-3-carboxylate [ACD/IUPAC Name]
naphthalen-1-yl 1-pentyl-1H-indazole-3-carboxylate


SDB-005  | SDB-005 Buy | SDB-005 For Sale | Buy SDB-005 USA

As of my last knowledge update in January 2022, SDB-005 is a synthetic cannabinoid that belongs to the indazole-based family of compounds. Synthetic cannabinoids are a class of psychoactive substances designed to mimic the effects of THC (tetrahydrocannabinol), the main psychoactive component of cannabis. These compounds are often created for research purposes, but some individuals may misuse them for recreational or intoxicating effects. It’s important to note that information on specific substances may have evolved since my last update.

SDB-005: An Overview

Chemical Structure:

SDB-005, also known as 1-pentyl-3-(2-iodobenzoyl)indole, features an indazole base with a substituted pentyl side chain and an iodine atom attached to the benzoyl group. The structural similarity to other synthetic cannabinoids implies that SDB-005 may interact with the same cannabinoid receptors in the brain and peripheral tissues as natural cannabinoids.


Synthetic cannabinoids like SDB-005 typically interact with the endocannabinoid system, which plays a crucial role in regulating various physiological processes, including mood, appetite, and pain sensation. These compounds bind to cannabinoid receptors, primarily CB1 and CB2, leading to altered neurotransmitter release and subsequent effects on the central nervous system.

Research Purposes:

SDB-005, like many other synthetic cannabinoids, is primarily synthesized for research purposes. Scientists and pharmacologists may use these substances to study the endocannabinoid system, potential medical applications, and the pharmacological effects of cannabinoids.

Potential Risks:

The recreational use of synthetic cannabinoids carries inherent risks. These substances can be unpredictable in their effects and may lead to adverse reactions, including anxiety, hallucinations, paranoia, and even more severe outcomes such as seizures or cardiovascular issues. Moreover, the lack of quality control and variability in the composition of synthetic cannabinoids purchased on the illicit market increases the risk of harm.

Legal Status:

SDB-005 legal status of synthetic cannabinoids varies from country to country and is subject to change. Many jurisdictions have classified these substances as controlled substances due to their potential for abuse and associated health risks.

Health Concerns:

The use of synthetic cannabinoids has been linked to a range of health issues. Emergency room visits related to the consumption of these substances often involve symptoms such as agitation, nausea, vomiting, hallucinations, and cardiovascular complications. Long-term health effects are not well understood due to limited research.


SDB-005 is one of many synthetic cannabinoids designed for research purposes. While these compounds contribute to scientific understanding of the endocannabinoid system, their recreational use poses considerable risks to health. The evolving nature of synthetic cannabinoid production and the lack of regulation underscore the importance of public awareness and ongoing research to address the potential dangers associated with these substances. It is crucial for individuals to be informed about the legal status and health risks associated with synthetic cannabinoids and to seek professional medical advice if needed.


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